Overall, the annual rate of self-inflicted injuries among both males and females ages 10 through 24 increased from 201.6 per 100,000 to 303.7 between 2001 and 2015. But among males, self-inflicted injury rates remained stable, the researchers found. Females alone contributed to the upward trend. The annual rate of self-inflicted injuries among females 10 through 24 rose from 245.5 per 100,000 in 2001 to 434 per 100,000 in 2015, an increase of 8.4% each year.